TY - JOUR AU - Marx, Christian AU - Schaarschmidt, Marc U. AU - Kirkpatrick, Joanna AU - Marx-Blümel, Lisa AU - Halilovic, Melisa AU - Westermann, Martin AU - Hoelzer, Doerte AU - Meyer, Felix B. AU - Geng, Yibo AU - Buder, Katrin AU - Schadwinkel, Hauke M. AU - Siniuk, Kanstantsin AU - Becker, Sabine AU - Thierbach, René AU - Beck, James F. AU - Sonnemann, Jürgen AU - Wang, Zhao-Qi PY - 2021 DA - 2021/03/20 TI - Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing’s sarcoma cells JO - Cell & Bioscience SP - 57 VL - 11 IS - 1 AB - Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE821 or the ATM inhibitor KU55933 were investigated for their effectiveness in Ewing's sarcoma cells. SN - 2045-3701 UR - https://doi.org/10.1186/s13578-021-00571-y DO - 10.1186/s13578-021-00571-y ID - Marx2021 ER -