Fig. 3
From: Neddylation regulation of mitochondrial structure and functions
MLN4924 regulates mitochondrial functions. MLN4924 induces mitochondrial fission-to-fusion conversion, increases mitochondrial copy number, oxygen consumption and ROS production, but inhibits mitochondrial membrane potential and ATP production. The proteins and signaling pathways involved in MLN4924-regulated mitochondrial functions are shown [30, 35]