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Fig. 3 | Cell & Bioscience

Fig. 3

From: Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor

Fig. 3

SARS-CoV-2 Orf6 is localized at the ER, autophagosome and lysosome membranes. a Schematic homology comparison between SARS-CoV Orf6 and SARS-CoV-2 Orf6. b, c Confocal analysis of SARS-CoV-2 protein Orf6 localization in COS-7 cells transfected with mCh-Orf6 together with CFP-LC3 (b), and mCe-lysosome20 (c). Scale bar, 10 μm. CFP, cyan fluorescent protein; LC3, microtubule-associated protein 1A/B-light chain 3; mCe, mCerulean; mCh, mCherry

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