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Table 1 γδT cells activation: ligands and receptors

From: In respond to commensal bacteria: γδT cells play a pleiotropic role in tumor immunity

Source Ligand Receptor References
Bacterial PAMP TLR2/5 [22]
IL-1 IL-1R [20]
Lipid antigen-CD1d Vδ1TCR [25, 26]
HMBPP-BTN3A1 Vδ2TCR [30, 92]
Cancer cell MICA/B, ULBP NKG2D [55, 57]
hMSH2 NKG2D [64]
Nectin-like 5 DNAM-1 [54]
B7-H6 NKp30 [59, 60]
Not known NKp46 [58]
F1-ATPase Vδ2TCR [61]
annexin A2 Vδ3TCR [62]
IPP-BTN3A1 Vδ2TCR [81, 84]