Fig. 6
From: Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
Predicted binding modes of ginkgolic acid to SARS-CoV-2 3CLpro (a) and PLpro (b). The 3CLpro (PDB ID: 6m2n) and PLpro (PDB code: 6WX4) are shown in green and orange cartoon respectively. The ginkgolic acid is shown in cyan sticks. The enlarged views represent ginkgolic acid in the active site with a view of the molecular surface of SARS-CoV-2 3CLpro (a) and PLpro (b). The His41-Cys145 dyad of 3CLpro and Cys111-His272-Asp286 triad of PLpro were indicated