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Fig. 7 | Cell & Bioscience

Fig. 7

From: The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation

Fig. 7

EGR2 overexpression alleviates asthma and lipid metabolism dysfunction induced by the YAP/HIF-1α/miR-182 axis in vivo. a the Th17 cell proportion in mouse spleen cells determined by flow cytometry; b the level of IL-17A in mouse serum measured by ELISA; c RORγt mRNA expression in mouse spleen cells determined by RT-qPCR; d Western blot analysis of RORγt protein in mouse spleen cells; e Th17 cell proportion in mouse lung tissues detected by flow cytometry. f Immunofluorescence staining showing the expression of α-SMA in the lung tissues of asthma mice

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