Fig. 1From: Deletion at an 1q24 locus reveals a critical role of long noncoding RNA DNM3OS in skeletal development Deletion of lncRNA-DNM3OS is associated with autosomal dominant inheritance of 1q24 deletion syndrome phenotypes. a Family tree of the proband (II-2). b Chromosomal maps of a cohort of 9 individuals with 1q24-25 deletions. c–f RT-qPCR quantifications of DNM3 mRNA, lncRNA-DNM3OS, miR-214, and miR-199 in the blood. The 3’ stem-loop primer for human miR-199 recognizes both miR-199a and miR-199b on chromosome 9, the latter of which is not affected by the deletion. g–m RT-qPCR quantifications of N-RAS, CBL, SHOC2, RAF1, BRAF, SOS1, and PTPN11 in the blood. One-way ANOVA test was used for statistical analysis. **P < 0.01, ***P < 0.001, and ns, not significantBack to article page