Skip to main content

Table 1 Human disorders linked to centrosome-phagy

From: Centrosome-phagy: implications for human diseases

Centrosome-phagy-associated human disorders

Relevant proteins

Ciliopathies

Polycystic kidney disease, retinitis pigmentosa, Joubert syndrome

OFD1 [98,99,100]

 

Polycystic kidney disease, Bardet–Biedl syndrome, Joubert syndrome, Meckel syndrome

PCM1 [69,70,71, 101]

Ageing

Huntington disease

PCM1 [102]

Cancer

Thyroid, renal, breast, ovarian and colon cancer

Cep55 [57, 95, 103,104,105]

 

Neuroblastoma

Cep63 [97]

 

Breast cancer

Cep131 [49]