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Fig. 3 | Cell & Bioscience

Fig. 3

From: Centrosome-phagy: implications for human diseases

Fig. 3

Different effects of PLK1 on autophagy in interphase and mitotic phase. In interphase, PLK1 can promote autophagy by phosphorylating Raptor to cause mTORC1 to disengage from lysosome. In mitotic phase, PLK1 promotes mTORC1 leading to up-regulation of p70S6K expression, thereby inhibiting autophagy

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Cell & Bioscience

ISSN: 2045-3701

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