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Fig. 6 | Cell & Bioscience

Fig. 6

From: Long non‐coding RNA NEAT1 transported by extracellular vesicles contributes to breast cancer development by sponging microRNA-141-3p and regulating KLF12

Fig. 6

NEAT1 silencing inhibits EVs-induced promotion of chemotherapy resistance of BC cells. a MTT assay was applied to check the proliferative inhibition of MCF-7 cells; si-NEAT1 treatment decreased cell viability and si-NEAT1 + EVs increased cell viability; b colony formation assay was utilized to measure colony formation ability of MCF-7 cells; c flow cytometry was applied for detection of MCF-7 cell apoptosis; d RT-qPCR was utilized to detect MDR1 mRNA expression in MCF-7 cells. Three independent experiments were performed; * p < 0.05; data were analyzed using two-way ANOVA, and Tukey’s multiple comparisons test was used for pairwise comparisons after ANOVA

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Cell & Bioscience

ISSN: 2045-3701

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