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Table 2 Correlation of PRIM1 expression with clinical features of 135 HCC patients

From: DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination

Characteristics   PRIM1 expression   P value
Patients Low High
Age (years)     
 < 60 104 51 53 0.801
 ≥ 60 31 16 15  
Sex     
 Male 113 55 58 0.614
 Female 22 12 10  
AFP level     
 < 20 30 19 11 0.089
 ≥ 20 105 48 57  
Tumor size (cm)     
 < 3 26 21 5 < 0.001
 ≥ 3 109 46 63  
Edmondson-Steiner grade     
 I + II 17 13 4 0.018
 III + IV 118 54 64  
Ascites     
 Absent 102 58 44 0.003
 Present 33 9 24  
TNM stage     
 I + II 57 41 16 < 0.001
 III + IV 78 26 52  
  1. PRIM1 DNA primase subunit 1, TNM tumor-node-metastasis