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Table 2 Correlation of PRIM1 expression with clinical features of 135 HCC patients

From: DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination

Characteristics

 

PRIM1 expression

 

P value

Patients

Low

High

Age (years)

    

 < 60

104

51

53

0.801

 ≥ 60

31

16

15

 

Sex

    

 Male

113

55

58

0.614

 Female

22

12

10

 

AFP level

    

 < 20

30

19

11

0.089

 ≥ 20

105

48

57

 

Tumor size (cm)

    

 < 3

26

21

5

< 0.001

 ≥ 3

109

46

63

 

Edmondson-Steiner grade

    

 I + II

17

13

4

0.018

 III + IV

118

54

64

 

Ascites

    

 Absent

102

58

44

0.003

 Present

33

9

24

 

TNM stage

    

 I + II

57

41

16

< 0.001

 III + IV

78

26

52

 
  1. PRIM1 DNA primase subunit 1, TNM tumor-node-metastasis