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Fig. 2 | Cell & Bioscience

Fig. 2

From: DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination

Fig. 2

Validating the expression features and prognostic values of PRIM1 in bioinformatic datasets. ad The expression levels of PRIM1 in HCC patients with different stages (grades), TP53 mutation, and metastasis status in TCGA LIHC dataset. e The expression levels of PRIM1 in HCC tissues and normal liver tissues in ICGC dataset. fh The expression levels of PRIM1 in HCC and pre-HCC cases in GSE89377 and GSE143233. ik The expression levels of PRIM1 in HCC cases or HCC cells with different sorafenib sensitivity in GSE63989, GSE 109211, and GSE62813. l The overall survival curves and recurrence free survival curves of HCC patients with high or low PRIM1 expression in entire cohort or stratified sub-groups of TCGA LIHC dataset. m The overall survival curves of HCC patients with high or low PRIM1 expression in entire cohort or stratified sub-groups of ICGC dataset. **P < 0.01; *P < 0.05

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