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Table 2 Comparison of Y haplogroups and SNV deletion pattern of AZFb-c amplicons of infertile men with “classical” and “non-classical” AZFb deletion

From: Human AZFb deletions cause distinct testicular pathologies depending on their extensions in Yq11 and the Y haplogroup: new cases and review of literature

AZFb-c amplicon Amplicon diagnostic SNV sites (A or B allele) WALBAE BRA1 GI2 AZG144
azoo-spermia
AZFG189 OAT AZFG372 azoo-spermia AZFG449 azoo-spermia AZFG606 crytozoo-spermia AZFG620 azoo-spermia AZFG637 Azoo-spermia AZFG712 OAT
Testicular pathology Meiotic arrest Meiotic arrest n.a. n.a. n.a. n.a. n.a. n.a. n.a.
AZFb deletion type Classical Non-classical Non-classical Non-classical Non-classical Non-classical Non-classical Non-classical Non-classical
Y haplogroups R1B* R1A1* I1* F* R1A1A1 R1A1A1 I1* R1A1A1 C*
b2 b2_AZFc-SFV B
g1 g1_AZFc-SFV B +
g1 g1_BPY2-1_SNV +
r1 DAZ-SNV_II A + + +
r2 DAZ -SNV_III A + + +
r2 DAZ-SNV_IV A +
gr1 Gr_AZFc-SFV A + + + + + +
b3 b3_AZFc-SFV B + + + + + +
yel1 Goly_SNV_I B + + + + + +
g2 g2_AZFc-SFV B + + + + + + +