Fig. 5

B lymphocyte infiltration in tumor tissues of male and female patients with PTC. a Two-dimensional distributions of B lymphocytes in the three groups. The B lymphocytes in different groups are displayed using different colors. b Five clusters of B lymphocytes were identified on the UMAP plot. c Bar graph of the frequency of the five cell clusters of B lymphocytes in the three groups. d Pseudotime plot of total B lymphocyte clusters of male and female patients with PTC. e Pseudotime plot of B lymphocytes. Cells from different groups were labeled with different colors. f Gene expression of representative genes in states 2 and 4 (shown in e) of B lymphocytes. A dot represents a cell, and different clusters are depicted using different colors. g, h The interactions between receptors and ligands in four cell clusters in male patients (g) and female patients (h) with PTC were analyzed by Spearman’s correlation coefficient based on gene expression intensity