Fig. 4

Interactions of malignant tumor cells with fibroblasts and endothelial cells in PTC. a Number of fibroblasts and endothelial cells that passed the quality filtering in the three groups. b Interactions between four types of cells in female patients and male patients. c, d The interactions between receptors and ligands in seven different cell clusters in female patients (c) and male patients (d) were analyzed by Spearman’s correlation coefficient based on gene expression intensity