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Fig. 7 | Cell & Bioscience

Fig. 7

From: Transcriptomic and metabolomic profiling reveal the p53-dependent benzeneacetic acid attenuation of silica‐induced epithelial–mesenchymal transition in human bronchial epithelial cells

Fig. 7

a Effects of benzeneacetic acid (concentration = 100 nM) on p53, E-Cadherin expression at indicated time points in p53-wt HBE cells. GAPDH was used as the control. b Effects of benzeneacetic acid (concentration = 100 nM) on p53, E-Cadherin expression at indicated time points in p53-KO HBE cells. c Effects of benzeneacetic acid (concentration = 100 nM) on the expression of p53, E-Cadherin, N-cadherin, Vimentin at indicated time points in p53-wt HBE cells post 12.5 µg/cm2 silica treatment. d Quantitative determination of relative E-Cadherin, N-cadherin, Vimentin expression in HBE p53-wt treated with or without benzeneacetic acid exposure at the indicated time points. GAPDH was used as control. Data are presented as means ± SD from three independent experiments: * p < 0.05 between different groups

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