Fig. 12

Homology M. brevicollis proteins to mammalian proteins, expression patterns of homologous genes, and association analyses. a Diagram depicting the strategy for analysis of protein homology between M. brevicollis and mammals, and the expression in vertebrate embryonic tissues. b Statistical graph showing numbers (percentages) of mammalian homologous proteins in M. brevicollis, and the numbers (percentages) of genes for the homologous proteins with neural specific expression in vertebrates. c–e Association between all mammalian homologous genes in M. brevicollis with GO (c), pathways (d) and human diseases (e). f–h Association between mammalian homologous genes in M. brevicollis with neural expression and GO (f), pathways (g) and human diseases (h). Cancers are highlighted with triangles. Circles indicate shared pathway terms between those for mammalian homologous genes in M. brevicollis and for neural genes in Fig. 11d