Fig. 8From: Probiotics mixture reinforces barrier function to ameliorate necrotizing enterocolitis by regulating PXR-JNK pathwaySchematic of the proposed mechanism of probiotic on enhancing intestinal epithelial barrier in NEC. The probiotics remodel the community of the intestinal microbiota, and induce the activation of PXR, which may subsequently inhibit the phosphorylation of JNK and elevate the expression of tight junction components to improve intestinal barrier functionBack to article page