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Fig. 4 | Cell & Bioscience

Fig. 4

From: Probiotics mixture reinforces barrier function to ameliorate necrotizing enterocolitis by regulating PXR-JNK pathway

Fig. 4

Probiotics regulated microbial community structure. a Uncluster heatmap of the top 30 OTUs. b Average abundance of the microbiota at the phylum level. c and d Alpha diversity, as represented by the Chao1 index and Shannon index. Boxes represent the interquartile range (IQR), with the inside line representing the median. e Effect of probiotic treatment on microbiota composition in principal coordinates analysis (Bray–Curtis dissimilarities). f Nonmetric multidimensional scaling (NMDS) based on the distance between the matrix Brary-Curtis. g and h Taxonomic biomarkers of three groups were identified by LDA scores using LEfSe and presented as a cladogram. Color signifies the group in which a differentially abundant taxon is enriched. Statistical analyses were performed with Student’s two-tailed unpaired t-test in (c) and (d). *p < 0.05; ***p < 0.001; n.s., not significant

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