Skip to main content

Advertisement

Table 1 Experimental studies that investigated the role of miRNAs involved in regulating apoptosis in endometriosis

From: Apoptotic functions of microRNAs in pathogenesis, diagnosis, and treatment of endometriosis

microRNAExpressionFunctionApplicationReferences
miR-33bDown-regulatedFacilitating caspase 3 activityTreatment and biomarker[96]
miR-191Up-regulatedInhibition of TNF-alpha induced apoptosis and might contribute malignant transformation of endometriosisTreatment and biomarker[97]
miR-503Down-regulatedTargeting BCL-2 mRNAsTreatment and biomarker[98]
miR-183Down-regulatedReducing apoptosisTreatment and biomarker[99]
miR-29cDown-regulatedTargeting c-JUN (a protein which regulates gene expression)Treatment and biomarker[100]
miR-148aAffecting BCL-2 expression and caspase-3/9 through G protein coupled estrogen receptor/miR148a/human leukocyte antigen G signaling pathwayTreatment[101]
miR-210Up-regulatedInhibition of apoptosis by targeting signal transducer and activator of transcription 3Treatment and biomarker[102]
miR-196bAffecting BCL-2 expression, activation of caspase-3 and caspase-7Treatment[103]
miR-363Down-regulatedInducing apoptosisTreatment and biomarker[104]
miR-21-5pAffecting the apoptotic potential of stromal cells.Treatment[92]
miR-9Down-regulatedAffecting BCL-2 expressionTreatment and biomarker[83]
miR181cNR4A-miR181c-Mst1 pathway regulates mitochondrial apoptosisTreatment[105]
miR-2861Down-regulatedUp-regulation of STAT3 and MMP2 and inducing apoptosisTreatment and biomarker[106]
miR-141-3pDown-regulation the expression of Bcl-2 and raising the expression of Bax and contributing to the apoptosis of ectopic ESCsTreatment[82]