Table 2 18 Mutations in exon 13, 14 or 17 of KIT were identified in 89 of 143 relapsed GISTs after Imatinib treatment
From: Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib
Mutation frequency | Mutations |
|---|---|
34 | V654A |
14 | N822K |
11 | Y823D |
8 | T670I |
5 | D820Y |
4 | D820G |
3 | D816H, D816E |
2 | C809G |
1 | 643insA, S709F, K786N/D816H, D820A, D820E, D820V, N822D, N822Y, A829P |