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Table 2 18 Mutations in exon 13, 14 or 17 of KIT were identified in 89 of 143 relapsed GISTs after Imatinib treatment

From: Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib

Mutation frequencyMutations
34V654A
14N822K
11Y823D
8T670I
5D820Y
4D820G
3D816H, D816E
2C809G
1643insA, S709F, K786N/D816H, D820A, D820E, D820V, N822D, N822Y, A829P