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Fig. 4 | Cell & Bioscience

Fig. 4

From: Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib

Fig. 4

Loss of PI3 kinase association inhibits secondary mutations of KIT mediated cell survival and proliferation. Ba/F3 cells stably expressing KIT mutants with or without PI3 kinase association were washed and cultured in the absence of IL-3 for 48 h, a apoptotic cells were examined by flow cytometry after staining with Annexin V-PE and b living cells were counted under microscope

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