Fig. 4
From: Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib
Loss of PI3 kinase association inhibits secondary mutations of KIT mediated cell survival and proliferation. Ba/F3 cells stably expressing KIT mutants with or without PI3 kinase association were washed and cultured in the absence of IL-3 for 48Â h, a apoptotic cells were examined by flow cytometry after staining with Annexin V-PE and b living cells were counted under microscope