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Fig. 1 | Cell & Bioscience

Fig. 1

From: Sperm-oocyte interplay: an overview of spermatozoon’s role in oocyte activation and current perspectives in diagnosis and fertility treatment

Fig. 1

The role of the sperm factors in the oocyte activation. In the normal activation process, the acrosome reaction (1) allows the exposure of PT for the fusion of the sperm membrane with the oocyte (2), starting in the equatorial segment and continuing to the PAS-PT, until penetration (3). SOAF are released into the ooplasm and triggers the Ca+ 2 oscillations via IP3. In the artificial oocyte activation, different strategies following ICSI could trigger Ca+ 2 oscillations, PLCζ microinjections (2a) or ionophore treatments (2b)

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Cell & Bioscience

ISSN: 2045-3701

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