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Table 1 Gene Ontology Biological Process analysis of for Ccm3ECKO mice RNA-Seq results

From: ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells

Pathway term Count p-value Genes
Hydrogen ion transmembrane transport 11 2.50E−13 NDUFA4, COX7A2, UQCRH, COX8A, COX7C, COX6B1, COX6A1, COX5A, UQCRQ, COX6C, UQCRB
Mitochondrial electron transport, cytochrome c to oxygen 8 3.14E−12 NDUFA4, COX8A, COX7C, COX6B1, COX6A1, COX5A, COX5B, COX6C
Mitochondrial ATP synthesis coupled proton transport 7 4.95E−10 ATP5E, ATP5J2, ATP5L, ATP5O, ATP5G2, ATP5G1, COX5B
ATP biosynthetic process 6 2.35E−07 ATP5E, ATP5J2, ATP5L, ATP5O, ATP5G2, ATP5G1
Mitochondrial electron transport, NADH to ubiquinone 6 3.50E−06 NDUFA4, NDUFB11, NDUFB5, NDUFA8, NDUFC2, NDUFA13
Generation of precursor metabolites and energy 5 1.17E−04 COX8A, COX7C, COX6A1, ATPIF1, COX6C
ATP synthesis coupled proton transport 4 1.50E−04 ATP5L, ATP5O, ATP5G2, ATP5G1
Mitochondrial respiratory chain complex I assembly 5 2.30E−04 NDUFB11, NDUFB5, NDUFA8, NDUFC2, NDUFA13
Cell–cell adhesion 8 3.07E−04 CCT8, WASF2, S100A11, RANBP1, EEF1D, PARK7, AHNAK, ANXA2
Mitochondrial electron transport, ubiquinol to cytochrome c 3 0.002261 UQCRH, UQCRQ, UQCRB
Angiogenesis 6 0.004235 PTPRB, CAV1, CLIC4, WASF2, ATPIF1, ANXA2