Skip to main content
Fig. 3 | Cell & Bioscience

Fig. 3

From: ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells

Fig. 3

Overexpression of ATPIF1 maintain the linear mitochondrial phenotype. a mitochondrial ATP concentration in HUVECs after siCCM3 and oeATPIF1 treatment, n = 3. b mitochondrial mito-stress assay in HUVECs after treatment by seahorse, cells were challenged with oligomycin (1 μM), FCCP (1 μM) and RO/AA(1 μM). c quantification of basal respiration, maximal respiration and spare respiration capacity in HUVECs after treatment, n = 6. d Immunofluorescence images and quantification (e) of mitochondria in HUVECs after treatment. f Western Blotting about mitochondrial fusion and fission proteins in HUVECs after treatment and quantification (g). *p < 0.05, **p < 0.01, ***p < 0.001. Scale bar, 50 μm

Back to article page