Fig. 4

BTX-A repressed LPS-induced releasing of cytokines in microglia via targeting TLR2/MyD88/SNAP23 signaling. a Expression of SNAP23 and p-SNAP23 in microglia were measured by western blotting assay. b qRT-PCR was performed to detect expression of genes of IL-1β, IL-6 and TNF-α. c Concentration of IL-1β, IL-6 and TNF-α in microglia were detected using ELISA assay. **P < 0.01 contrasted with Ctrl group, ^##P < 0.01 contrasted with LPS group, and ^$$P < 0.01 compared with LPS + BTX-A group