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Fig. 3 | Cell & Bioscience

Fig. 3

From: Botulinum toxin type A alleviates neuropathic pain and suppresses inflammatory cytokines release from microglia by targeting TLR2/MyD88 and SNAP23

Fig. 3

BTX-A restrained the effect of LPS on TLR2, MyD88, SNAP23 and pro-inflammatory factors expression. Microglias were co-treated with LPB and BTX-A. a Expression of TLR2, MyD88, p-SNAP23 and SNAP23 were measured by western blotting assay. b Expression of IL-1β, IL-6 and TNF-α genes were examined using qRT-PCR. c ELISA assay was performed to measure the concentration of IL-1β, IL-6 and TNF-α in cell culture medium. **P < 0.01 contrasted with Ctrl group and ##P < 0.01 contrasted with LPS group. The cells in Ctrl group was treated with nothing

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Cell & Bioscience

ISSN: 2045-3701

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