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Fig. 1 | Cell & Bioscience

Fig. 1

From: Botulinum toxin type A alleviates neuropathic pain and suppresses inflammatory cytokines release from microglia by targeting TLR2/MyD88 and SNAP23

Fig. 1

Expression of TLR2 and MyD88 were suppressed by BTX-A. SD rats were randomly divided into four groups: Sham, CCI-induced NP, BTX-A-10 (rats were given 10 U/kg of BTX-A following CCI) and BTX-A-20 (rats were given 20 U/kg of BTX-A following CCI). a Expression of TLR2, TLR4 and MyD88 mRNAs were measured by qRT-PCR. b Expression of TLR2, TLR4 and MyD88 proteins were examined using western blotting assay. **P < 0.01 compared with Sham group, #P < 0.05 and ##P < 0.01 compared with NP group

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