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Fig. 2 | Cell & Bioscience

Fig. 2

From: CXCR7: a β-arrestin-biased receptor that potentiates cell migration and recruits β-arrestin2 exclusively through Gβγ subunits and GRK2

Fig. 2

CXCR7 and CXCR4 compete with each other for SDF-1α ligand specificity. a–c NanoBiT receptor/β-arrestin2 constructs were co-expressed with other receptors governed by different promoters as described for each graph. d–f Graphs of maximum luminescence activities in each experiment from (a–c). g Transcriptional activities of each promoter. HEK293 cells expressing GFP governed by the CMV (CMV/GFP), Ubiquitin C (UbiC/GFP), or herpes simplex virus-thymidine kinase (HSV-tk/GFP) promoter were lysed and used for western blotting with anti-GFP antibodies. Results are the average of three independent experiments. Values are presented as the mean ± SD

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Cell & Bioscience

ISSN: 2045-3701

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