Significant transcriptomic changes are associated with differentiation of bone marrow-derived mesenchymal stem cells into neural progenitor-like cells in the presence of bFGF and EGF

Table 2 List of pathways and biological process

MSigDB Gene Set	Number	ES	NES	FDR q-value
BIOCARTA_INTEGRIN_PATHWAY	19	− 0.748	− 1.978	0.004
REACTOME_CELL_CYCLE_CHECKPOINTS	160	− 0.432	− 1.698	0.039
GO_ACTIN_FILAMENT_BASED_PROCESS	435	− 0.370	− 1.613	0.048
GO_MITOTIC_CYTOKINESIS	32	− 0.525	− 1.567	0.056
GO_MICROTUBULE_CYTOSKELETON_ORGANISATION_INVOLVED_IN_MITOSIS	66	− 0.430	− 1.512	0.064
REACTOME_CELL_CYCLE	343	− 0.318	− 1.383	0.121
KEGG_CELL_CYCLE	80	− 0.357	− 1.285	0.193
GO_CELL_CYCLE_G2_M_PHASE_TRANSITION	162	− 0.315	− 1.244	0.193

Reported are the terms significantly enriched (FDR < 0.25) in MSCs. ES enrichment score, NES normalised enrichment score

ISSN: 2045-3701