Fig. 5

Phloretin (PT) modulated lipogenesis and lipolysis gene expression in liver tissue. a Expression levels of Srebp-1c, b C/EBPβ, c FAS, d ATGL, e HSL, f CPT-1, g CPT-2, h PPAR-α, and i Sirt-1 according to real-time PCR. Fold-changes in expression were measured relative to β-actin expression (internal control). Three independent experiments were analyzed and the data presented as the mean ± SEM; n = 10. *P < 0.05, **P < 0.01 compared to HFD-induced obesity. ^#P < 0.05, ^##P < 0.01 compared to the Normal group