Table 5 Comparison between BMSCs, UC-MSCs and ADSCs for the treatment of SCI
From: Treatment of spinal cord injury with mesenchymal stem cells
Characteristics | BMSCs | UC-MSCs | ADSCs |
|---|---|---|---|
Harvesting procedure | Invasive | None invasive | Invasive |
Easiness to isolate and culture | Easy | Easy | Easy |
Effect of age on cell quantity and quality | Quantity and quality decline with age | Unaffected | Quantity and quality decline with age |
Potency to differential into nerve cells | Lower | Higher | Lower |
Cell renewal | Lower proliferative potential | Higher proliferative potential | Lower proliferative potential |
Expression of embryonic markers | Lower | Higher | Lower |
Immune modulatory property | Good | Good | Good |
Allogeneic cell rejection | No | No | No |
Ethical issues | No | No | No |
Risk of tumorigenicity | Very low | Very low | Very low |