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TableĀ 5 Comparison between BMSCs, UC-MSCs and ADSCs for the treatment of SCI

From: Treatment of spinal cord injury with mesenchymal stem cells

Characteristics

BMSCs

UC-MSCs

ADSCs

Harvesting procedure

Invasive

None invasive

Invasive

Easiness to isolate and culture

Easy

Easy

Easy

Effect of age on cell quantity and quality

Quantity and quality decline with age

Unaffected

Quantity and quality decline with age

Potency to differential into nerve cells

Lower

Higher

Lower

Cell renewal

Lower proliferative potential

Higher proliferative potential

Lower proliferative potential

Expression of embryonic markers

Lower

Higher

Lower

Immune modulatory property

Good

Good

Good

Allogeneic cell rejection

No

No

No

Ethical issues

No

No

No

Risk of tumorigenicity

Very low

Very low

Very low