Fig. 3
From: Rap1b but not Rap1a in the forebrain is required for learned fear
Rap1 is not required for retrieval-induced c-Fos expression in basolateral amygdala. a A schematic of the experimental configuration. b Representative images showing c-Fos expression in basolateral amygdala of Rap1af/f and Rap1a cKO mice. Slices were stained with anti-c-Fos (red) antibody, nuclei were showed by DAPI (blue). Scale bar, 30 μm. c Quantitative analysis of data in b. c-Fos expressions were normalized to Rap1af/f CS only group. For CS only group: n = 12 slices from 4 mice per group. For learning group: n = 16 slices from 4 mice per group. d Representative images showing c-Fos expression in basolateral amygdala of Rap1bf/f and Rap1b cKO mice. Scale bar, 30 μm. e Quantitative analysis of data in d. c-Fos expressions were normalized to Rap1bf/f CS only group. For CS only group: n = 13 slices from 4 mice per group. For learning group: n = 11 slices from 4 mice per group. Data are presented as mean ± SEM; **p < 0.01, ***p < 0.001