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Fig. 5. | Cell & Bioscience

Fig. 5.

From: Disruption in iron homeostasis and impaired activity of iron-sulfur cluster containing proteins in the yeast model of Shwachman-Diamond syndrome

Fig. 5.

Prior deletion of POR1 restores defects observed in cells lacking Sdo1p. a Intracellular iron levels of WT, sdo1∆, por1∆ and sdo1∆por1∆, as indicated, were examined as described in Fig. 1. Data were from three independent experiments. bd The induction of FET3-lacZ and activities of aconitase and succinate dehydrogenase were monitored as described in Fig. 4. Indicated strains were cultured in YPD media with 2% glucose for 40 hours until reaching stationary phase. Data were from three independent experiments. Values are the mean + SD. ***P < 0.001 and **P < 0.01 determined using Student’s T-test compared between the means of two indicated groups

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