Table 3 Univariate and Multivariate Analysis of Variables Associated with Overall Survival in Patients with hilar cholangiocarcinoma
Variable | No. | Mean survival (years) | P value (univariate) | P value (multivariate) | Hazard ratio | 95% CI |
|---|---|---|---|---|---|---|
Positive margin | ||||||
 No | 83 | 2.46 | 0.013 |  |  |  |
 Yes | 35 | 1.64 |  |  |  |  |
T stage | ||||||
 T1/T2 | 70 | 2.51 | 0.019 |  |  |  |
 T3/T4 | 48 | 1.75 |  |  |  |  |
Regional lymph nodes positive | ||||||
 No | 55 | 2.72 | 0.001 |  |  |  |
 Yes | 63 | 1.68 |  |  |  |  |
TNM stage | ||||||
 I/II | 37 | 2.96 | 0.003 |  |  |  |
 III/IV | 81 | 1.82 |  |  |  |  |
RPL34 | ||||||
 Negative | 27 | 3.63 | < 0.001 | 0.001 | 0.254 | 0.120–0.538 |
 Positive | 91 | 1.70 |  |  |  |  |
Differentiation | ||||||
 Well/moderate | 10 | 3.10 | 0.025 |  |  |  |
 Poor/undifferentiated | 108 | 2.02 |  |  |  |  |