Fig. 7

Proposed role of MAPK7 in growth plate development. a The expression patterns of MAPK7 and p-MAPK7 in the growth plate. The depth of color represents the expression levels of corresponding markers. RZ, resting zone; PZ, proliferative zone; HZ, hypertrophic zone. b A schematic model summarizing the role of MAPK7 in the regulation of growth plate development and modulating HIF1α signaling for hypoxic adaptation