Fig. 1From: Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxiaLoss of MAPK7 in chondrocytes caused growth restriction and short limbs in postnatal mice. a Phenotype of Mapk7 CKO and CON littermates at P21. Scale bar, 1 cm. b Analysis of body length of Mapk7 CKO and CON mice at P21 (n = 3). *P < 0.05 (Student’s t test). Data are presented as mean ± SD. c Comparison of body weight between CON and Mapk7 CKO mice at various time points. Male and female mice were combined (n = 4). *P < 0.05 (paired-sample t test). Data are presented as mean ± SD. d Representative image and (e, f) quantification analysis of limb bones from 60-day-old CON and Mapk7 CKO mice (n = 6). Scale bar, 5 mm. *P < 0.05 (Student’s t test). N.S., not significant. Data are presented as mean ± SDBack to article page