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Fig. 1 | Cell & Bioscience

Fig. 1

From: Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia

Fig. 1

Loss of MAPK7 in chondrocytes caused growth restriction and short limbs in postnatal mice. a Phenotype of Mapk7 CKO and CON littermates at P21. Scale bar, 1 cm. b Analysis of body length of Mapk7 CKO and CON mice at P21 (n = 3). *P < 0.05 (Student’s t test). Data are presented as mean ± SD. c Comparison of body weight between CON and Mapk7 CKO mice at various time points. Male and female mice were combined (n = 4). *P < 0.05 (paired-sample t test). Data are presented as mean ± SD. d Representative image and (e, f) quantification analysis of limb bones from 60-day-old CON and Mapk7 CKO mice (n = 6). Scale bar, 5 mm. *P < 0.05 (Student’s t test). N.S., not significant. Data are presented as mean ± SD

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