Skip to main content
Fig. 4 | Cell & Bioscience

Fig. 4

From: Overexpression of pyruvate dehydrogenase phosphatase 1 promotes the progression of pancreatic adenocarcinoma by regulating energy-related AMPK/mTOR signaling

Fig. 4

PDP1 induced PDAC cell proliferation and migration by inducing intracellular ATP. a PDP1 overexpression induced intracellular ATP content, while its knockdown reduced ATP levels. Supplementation of an alternative substrate of ATP production, acetate, restored cell proliferation (b), colony formation (c) and migration of PDP1 knockdown PDAC cells (d). ***p < 0.001

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us