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Fig. 2 | Cell & Bioscience

Fig. 2

From: Overexpression of pyruvate dehydrogenase phosphatase 1 promotes the progression of pancreatic adenocarcinoma by regulating energy-related AMPK/mTOR signaling

Fig. 2

PDP1 regulated PDAC cell proliferation and migration in vitro. a Transfection of the PDP1 ORF clone or shRNA regulated endogenous expression of PDP1 in PDAC cells. b Overexpression of PDP1 promoted PDAC cell proliferation, while PDP1 suppressed PDAC cell proliferation. c Overexpression of PDP1 promoted colony formation of PDAC cells, while PDP1 suppressed PDAC cell colony number. d Overexpression of PDP1 promoted PDAC cell migration, while PDP1 suppressed PDAC cell migration. ***p < 0.001

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