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Fig. 1 | Cell & Bioscience

Fig. 1

From: Overexpression of pyruvate dehydrogenase phosphatase 1 promotes the progression of pancreatic adenocarcinoma by regulating energy-related AMPK/mTOR signaling

Fig. 1

PDP1 was overexpressed in PDAC. Data were retrieved from the GEO database, and PDP1 was found to be overexpressed in PDAC tissues compared with normal pancreatic tissues in (a) GSE15471 and (b) GSE28735. c Immunohistochemical staining of PDP1 was retrieved from the Human Protein Atlas, which suggested that PDP1 protein expression was upregulated in PDAC tissues. Survival of PDAC patients was retrieved from TGCA database, and patients with PDP1 expression above the median level had poor (d) overall survival and (e) disease-free survival. f Surviving PDAC patients had lower expression of PDP1 than the censored patients

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