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Fig. 9 | Cell & Bioscience

Fig. 9

From: Nrf2 promotes esophageal squamous cell carcinoma (ESCC) resistance to radiotherapy through the CaMKIIα-associated activation of autophagy

Fig. 9

Overexpression of Nrf2 increases radiation resistance of Ec109 xenograft in nude mice. The growth images of wild-type (WT) and Nrf2-overexpressed (Nrf2-OE) Ec109 tumor in nude mice administrated with or without irradiation (IR, 6 Gy). a The growth curves of WT and Nrf2-OE Ec109 tumor in nude mice administrated with or without irradiation (IR, 6 Gy). b The expressions of Nrf2, CaMKIIα, LC3-II, and Ki-67 were examined by immunohistochemistry staining in the Ec109 tumor tissues of nude mice. c All results are presented as the mean ± SEM of 6 mice in each group. The differences among the groups were obtained using Analysis of Variance (ANOVA). **P < 0.01

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