Fig. 2

The overexpression of Nrf2 is related to the radiation resistance of ESCC cells. The radiosensitivity of wild-type (WT) and Nrf2-overexpressed (Nrf2-OE) Ec109 and KYSE-30 cells was detected by Cell counting kit-8 (CCK-8) assay (a) and colony formation test (b for Ec109 cells, c for KYSE-30 cells). Representative pictures of colony formation assay and cell survival curves (b, c) are shown. All results are presented as the mean ± SEM from three repeated experiments. The differences in the two groups were obtained using Student’s t-test. *P < 0.05 and **P < 0.01