Fig. 4
From: Exosomal cargos modulate autophagy in recipient cells via different signaling pathways
A schematic diagram of signaling pathways in exosome-mediated autophagy inside target cell. Different signaling pathways are involved in exosome-mediated autophagy. Exosomes may contribute to autophagy flux of target cells via directly delivering cargo into the cytoplasm or via interacting with such receptors as EGFR and TLR1/2/4/6 located on the plasma membrane. Other potential signaling pathways may be induced by exosomes. Red color for Akt/mTOR signaling pathway, Blue color for Toll-like receptor-ligand signal pathway, Light purple color for AMPK/mTOR signal pathway