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Table 5 Univariate and multivariate analysis of CD68+ TAMs and clinicopathological factors affecting survival of GC in subtype of diameter ≥ 5 cm

From: Inverse correlation between Interleukin-34 and gastric cancer, a potential biomarker for prognosis

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

p-value

HR (95% CI)

p-value

CD68 (low/high)

2.222 (1.014–4.872)

0.046

1.781 (0.776–4.087)

0.173

Gender

 Female/male

0.778 (0.349–1.733)

0.539

  

Age (≤ 60/> 60)

0.924 (0.442–1.928)

0.832

  

Lymph node metastasis

 No/yes

0.820 (0.311–2.165)

0.689

  

Tumour differentiation

 Low (reference)

1

0.533

  

 High

1.100 (0.144–8.377)

0.927

  

 Moderate

0.636 (0.284–1.426)

0.272

  

Invasion depth

 T4

1

0.548

  

 T2

0.610 (0.131–2.836)

0.529

  

 T3

0.645 (0.286–1.453)

0.290

  

TNM

 IV (reference)

1

0.007

1

0.025

 II

0.095 (0.022–0.412)

0.002

0.125 (0.027–0.568)

0.007

 III

0.157 (0.040–0.616)

0.008

0.184 (0.047–0.724)

0.015

  1. Bold italic values indicate significance (p < 0.05)