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Table 5 Univariate and multivariate analysis of CD68+ TAMs and clinicopathological factors affecting survival of GC in subtype of diameter ≥ 5 cm

From: Inverse correlation between Interleukin-34 and gastric cancer, a potential biomarker for prognosis

Variables Univariate analysis Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
CD68 (low/high) 2.222 (1.014–4.872) 0.046 1.781 (0.776–4.087) 0.173
Gender
 Female/male 0.778 (0.349–1.733) 0.539   
Age (≤ 60/> 60) 0.924 (0.442–1.928) 0.832   
Lymph node metastasis
 No/yes 0.820 (0.311–2.165) 0.689   
Tumour differentiation
 Low (reference) 1 0.533   
 High 1.100 (0.144–8.377) 0.927   
 Moderate 0.636 (0.284–1.426) 0.272   
Invasion depth
 T4 1 0.548   
 T2 0.610 (0.131–2.836) 0.529   
 T3 0.645 (0.286–1.453) 0.290   
TNM
 IV (reference) 1 0.007 1 0.025
 II 0.095 (0.022–0.412) 0.002 0.125 (0.027–0.568) 0.007
 III 0.157 (0.040–0.616) 0.008 0.184 (0.047–0.724) 0.015
  1. Bold italic values indicate significance (p < 0.05)