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Table 3 Univariate and multivariate analysis of CD68+ TAMs and clinicopathological factors affecting survival of patients in T3 stage of GC

From: Inverse correlation between Interleukin-34 and gastric cancer, a potential biomarker for prognosis

Variables Univariate analysis Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
CD68 (low/high) 3.080 (1.135–8.360) 0.027 5.471 (1.825–16.397 0.002
Gender
 Female/male 0.638 (0.216–1.886) 0.416   
 Age (≤ 60/> 60) 1.052 (0.479–2.310) 0.900   
 Diameter(< 5/≥ 5, cm) 0.464 (0.196–1.100) 0.081   
Lymph node metastasis
 No/yes 0.407 (0.167–0.993) 0.048 0.363 (0.123–1.075) 0.067
Tumour differentiation
 Low (reference) 1 0.436   
 High 0.269 (0.035–2.059) 0.206   
 Moderate 0.825 (0.348–1.955) 0.663   
TNM
 IV (reference) 1 0.019 1 0.007
 II 0.140 (0.029–0.683) 0.015 0.061 (0.011–0.351) 0.002
 III 0.337 (0.070–1.619) 0.174 0.101 (0.016–0.634) 0.014
  1. Bold italic values indicate significance (p < 0.05)