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Table 2 Univariate and multivariate analysis of IL-34 and clinicopathological factors affecting survival of patients with GC

From: Inverse correlation between Interleukin-34 and gastric cancer, a potential biomarker for prognosis

Variables Univariate analysis Multivariate analysis
HR (95% CI) p-value HR (95% CI) p-value
IL-34 (low/high) 2.205 (1.072–4.537) 0.032 1.457 (0.639–3.325) 0.371
Gender
 Female/male 0.886 (0.443–1.775) 0.733   
Age (≤ 60/> 60) 1.058 (0.573–1.955) 0.857   
Diameter (< 5/≥ 5, cm) 0.363 (0.189–0.698) 0.002 0.495 (0.217–1.129) 0.095
Lymph node metastasis
 No/yes 0.267 (0.122–0.582) 0.001 0.772 (0.274–2.173) 0.624
Tumour differentiation
 Low (reference) 1 0.545   
 High 0.725 (0.218–2.411) 0.600   
 Moderate 0.693 (0.349–1.375) 0.294   
Invasion depth
 T4 1 0.142 1 0.955
 T1 0.000 (0.000–) 0.977 0.900 (0.000–) 1.000
 T2 0.261 (0.084–0.808) 0.020 1.528 (0.326–7.165) 0.591
 T3 0.750 (0.380–1.478) 0.405 1.049 (0.463–2.378) 0.909
TNM
 IV (reference) 1 0.000 1 0.001
 I 0.000 (0.000–) 0.966 0.000 (0.000–) 0.969
 II 0.085 (0.028–0.260) 0.000 0.075 (0.021–0.270) 0.000
 III 0.195 (0.068–0.559) 0.002 0.154 (0.047–0.503) 0.002
  1. Bold italic values indicate significance (p < 0.05)