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Fig. 4 | Cell & Bioscience

Fig. 4

From: Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway

Fig. 4

Inhibition of Wnt signaling pathway could suppress the function of IR-MSCs. CD133+ Huh7 was pretreated by PRI-724 and co-cultured with MSCs and IR-MSCs for 7 days. a Expression of CD133, Wnt3a and β-catenin in CD133+ Huh7. b Colony formation of CD133+ Huh7. c Quantification of panel B. d Tumorigenesis of CD133+ Huh7 in nude mice. e Tumor volume and weight were measured

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Cell & Bioscience

ISSN: 2045-3701

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