From: MicroRNA let-7b inhibits cell proliferation via upregulation of p21 in hepatocellular carcinoma
Characteristics | Let-7b low (n = 47) | Let-7b high (n = 47) | P value |
---|---|---|---|
Age (years) (mean ± SD) | 49.8 ± 9.3 | 51.8 ± 11.6 | 0.354 |
Gender (Male/Female) | 40/7 | 39/8 | 0.778 |
HBsAg (positive/negative) | 40/7 | 39/8 | 0.778 |
Cirrhosis (positive/negative) | 26/21 | 19/28 | 0.148 |
Child–Pugh classification(A/B) | 46/1 | 45/2 | 0.554 |
AFP (ng/mL) | Â | Â | 0.626 |
 ≥ 400 | 35 | 37 |  |
 < 400 | 12 | 10 |  |
Biggest tumor diameter (cm) (mean ± SD) | 6.8 ± 4.6 | 6.0 ± 4.8 | 0.363 |
Blood transfusion (positive/negative) | 8/39 | 6/41 | 0.562 |
Microvascular invasion (positive/negative) | 18/29 | 17/30 | 0.831 |
Portal vein invasion (positive/negative) | 4/43 | 2/45 | 0.399 |
Tumor capsule (positive/negative) | 9/38 | 10/37 | 0.797 |
BCLC stage | Â | Â | 0.779 |
 A | 14 | 17 |  |
 B | 29 | 27 |  |
 C | 4 | 3 |  |