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Fig. 2 | Cell & Bioscience

Fig. 2

From: MicroRNA let-7b inhibits cell proliferation via upregulation of p21 in hepatocellular carcinoma

Fig. 2

Let-7b overexpression decreased the proliferation of HCC cells. a RT-PCR was performed to detect let-7b expression in normal liver cells and HCC cell lines. Data from three replicates are shown as the means (± SD). *P < 0.05, **P < 0.01. b, c Let-7b expression was tested by RT-PCR when HepG2 and QGY-7703 cell lines were transfected with negative control (NC) and let-7b mimics (Let-7b). Data from three replicates are shown as the means (± SD). **P < 0.01. d, e CCK-8 assay was used to detect cell proliferation of HepG2 and QGY-7703 cell lines treated with negative control (NC) and let-7b mimics (Let-7b). Data from three replicates are shown as the means (± SD). **P < 0.01. f, g Flow cytometric analysis was performed to test the cell cycles of HepG2 and QGY-7703 cell lines treated with negative control (NC) and let-7b mimics (Let-7b). Data from three replicates are shown as the means (± SD). *P < 0.05

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