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Table 1 Groups and treatments used in the animal experiments

From: Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia

Experimental groups

Experimental treatments

Sham

Intracerebral cannula + electrocoagulation of the vertebral arteries + PBS (total 7.5 μl)

I/R

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + PBS (total 7.5 μl)

DADLE

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 2.5 nmol DADLE (total 7.5 μl)

DADLE + naltrindole

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 2.5 nmol DADLE + 2.5 nmol naltrindole (total 7.5 μl)

DADLE + 3-MA

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 2.5 nmol DADLE + 600 nmol 3-MA (total 7.5 μl)

DADLE + compound C

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 2.5 nmol DADLE + 100 nmol compound C (total 7.5 μl)

A769662

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 100 nmol A769662 (total 7.5 μl)

Compound C

Intracerebral cannula + electrocoagulation of the vertebral arteries + carotid artery occlusion + 100 nmol compound C (total 7.5 μl)

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Cell & Bioscience

ISSN: 2045-3701

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